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Evaluation of the relationship between serum levels of zinc, vitamin B12, vitamin D, and clinical outcomes in patients with COVID-19

Shakeri et al., Journal of Medical Virology, doi:10.1002/jmv.27277
Aug 2021  
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Zinc for COVID-19
2nd treatment shown to reduce risk in July 2020
 
*, now known with p = 0.0000013 from 44 studies, recognized in 10 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,900+ studies for 60+ treatments. c19early.org
Retrospective 293 hospitalized patients in Iran showing lower levels of zinc, vitamin B12, and vitamin D in patients that died, with statistical significance reached only for zinc.
Study covers vitamin B12, zinc, and vitamin D.
Shakeri et al., 18 Aug 2021, Iran, peer-reviewed, 7 authors.
This PaperZincAll
Evaluation of the relationship between serum levels of zinc, vitamin B12, vitamin D, and clinical outcomes in patients with COVID‐19
Habibesadat Shakeri, Amir Azimian, Hamed Ghasemzadeh‐moghaddam, Mohammadreza Safdari, Mehdi Haresabadi, Tahereh Daneshmand, Hasan Namdar Ahmadabad
Journal of Medical Virology, doi:10.1002/jmv.27277
Due to the known anti-inflammatory and antiviral effects of zinc, 25(OH)D, and vitamin B12, in this study, we explored the association between serum levels of these micronutrients in coronavirus disease 2019 (COVID-19) patients at the time of admission and the clinical outcomes. This study was carried out on 293 patients with COVID-19, who were hospitalized at Imam Hassan hospital (Bojnourd, Iran). We collected demographic data, clinical characteristics, values of serum biochemical parameters in the first week of admission, and clinical outcomes from electronic medical records. We also measured serum levels of zinc, 25(OH)D, and vitamin B12 ORCID
CONFLICT OF INTERESTS The authors declare that there are no conflicts of interest. AUTHOR CONTRIBUTIONS The author who conceived the study: Habibesadat Shakeri. Authors
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