Retrospective 79 hospitalized patients in Belgium, showing mortality associated with zinc and selenium deficiency.
Laing et al., 9/22/2021, retrospective, Belgium, Europe, peer-reviewed, 11 authors.
risk of death, 79.0% lower, RR 0.21, p = 0.01, high zinc levels 3 of 49 (6.1%), low zinc levels 7 of 24 (29.2%).
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.