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0 0.5 1 1.5 2+ Mortality 20% unadjusted Improvement Relative Risk c19zinc.com Kumar et al. Zinc for COVID-19 Prophylaxis Favors zinc Favors control
Kumar, 105 patient zinc prophylaxis study: 20% lower mortality [p=0.71] https://c19p.org/kumar4
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Role of Zinc and Clinicopathological Factors for COVID-19-Associated Mucormycosis (CAM) in a Rural Hospital of Central India: A Case-Control Study
Kumar et al., Cureus, doi:10.7759/cureus.22528
23 Feb 2022    Source   PDF   Share   Tweet
Case control study of 105 COVID-19 patients in India, 55 with mucormycosis and 50 without, showing zinc prophylaxis and diabetes both associated with mucormycosis in unadjusted results. This is likely confounded because zinc supplementation is commonly used with diabetes [academic.oup.com], and Arora et al. show lower risk of mucormycosis with zinc prophylaxis, aOR 0.05 [0.01–0.19] [Arora]. There was no significant difference in mortality based on zinc prophylaxis in unadjusted results.
risk of death, 20.0% lower, RR 0.80, p = 0.71, treatment 6 of 75 (8.0%), control 3 of 30 (10.0%), NNT 50, unadjusted.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
Kumar et al., 2/23/2022, retrospective, India, South Asia, peer-reviewed, 10 authors, study period June 2021 - August 2021.
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