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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Severe case 82% Improvement Relative Risk c19zinc.com/goncalves.html Favors zinc Favors control
23 December 2020 - Analysis of outcomes based on serum levels
Association Between Low Zinc Levels and Severity of Acute Respiratory Distress Syndrome by New Coronavirus SARS-CoV-2
Gonçalves et al., Nutrition in Clinical Practice, doi:10.1002/ncp.10612 (Peer Reviewed)
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Retrospective 169 ICU patients in Brazil, 214 with low zinc levels, showing an association between low zinc levels and severe ARDS. CAAE 30608,020.9.0000.8114.
risk of severe case, 82.3% lower, RR 0.18, p < 0.001, high zinc levels 7 of 55 (12.7%), low zinc levels 145 of 214 (67.8%), NNT 1.8, adjusted per study, odds ratio converted to relative risk, ≥70 μg/dL, logistic regression.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Gonçalves et al., 12/23/2020, retrospective, Brazil, South America, peer-reviewed, 9 authors.
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