Clinical features, demography and predictors of outcomes of SARS-CoV-2 infection in a tertiary care hospital in India

8/12 Late treatment study

Elavarasi et al., medRxiv, doi:10.1101/2021.08.10.21261855 (Preprint)
Clinical features, demography and predictors of outcomes of SARS-CoV-2 infection in a tertiary care hospital in India - a cohort study

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Retrospective 2017 hospitalized patients in India, showing lower mortality with zinc treatment.

Elavarasi et al., 8/12/2021, retrospective, India, South Asia, preprint, 26 authors.

risk of death, 65.1% lower, RR 0.35, p < 0.001, treatment 486, control 1201, adjusted per study, odds ratio converted to relative risk, model 4, multivariate logistic regression, control prevalence approximated with overall prevalence.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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