Retrospective 2017 hospitalized patients in India, showing lower mortality with zinc treatment.
Elavarasi et al., 8/12/2021, retrospective, India, South Asia, preprint, 26 authors.
risk of death, 65.1% lower, RR 0.35, p < 0.001, treatment 486, control 1201, adjusted per study, odds ratio converted to relative risk, model 4, multivariate logistic regression, control prevalence approximated with overall prevalence.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.