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0 0.5 1 1.5 2+ Progression 33% Improvement Relative Risk ICU time 6% c19zinc.com Darban et al. Zinc for COVID-19 RCT ICU PATIENTS Favors zinc Favors control
Darban, 20 patient zinc ICU RCT: 33% lower progression [p=1] and 6% lower ICU admission [p=0.3] https://c19p.org/darbanz
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Efficacy of High Dose Vitamin C, Melatonin and Zinc in Iranian Patients with Acute Respiratory Syndrome due to Coronavirus Infection: A Pilot Randomized Trial
Darban et al., Journal of Cellular & Molecular Anesthesia, doi:10.22037/jcma.v6i2.32182
15 Dec 2020    Source   PDF   Share   Tweet
Small RCT in Iran with 20 ICU patients, 10 treated with high-dose vitamin C, melatonin, and zinc, not showing significant differences. IRCT20151228025732N52.
risk of progression, 33.3% lower, RR 0.67, p = 1.00, treatment 2 of 10 (20.0%), control 3 of 10 (30.0%), NNT 10.
ICU time, 6.0% lower, relative time 0.94, p = 0.30, treatment 10, control 10.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Darban et al., 12/15/2020, Randomized Controlled Trial, Iran, Middle East, peer-reviewed, 8 authors, this trial uses multiple treatments in the treatment arm (combined with melatonin and vitamin C) - results of individual treatments may vary.
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