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0 0.5 1 1.5 2+ Hospitalization time 30% Improvement Relative Risk Zinc for COVID-19  Alahmari et al.  LATE TREATMENT Is late treatment with zinc beneficial for COVID-19? Retrospective 977 patients in Saudi Arabia (May - July 2020) Shorter hospitalization with zinc (p<0.000001) c19early.org Alahmari et al., Healthcare, June 2022 Favors zinc Favors control

Factors Associated with Length of Hospital Stay among COVID-19 Patients in Saudi Arabia: A Retrospective Study during the First Pandemic Wave

Alahmari et al., Healthcare, doi:10.3390/healthcare10071201
Jun 2022  
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Zinc for COVID-19
2nd treatment shown to reduce risk in July 2020
 
*, now known with p = 0.0000013 from 44 studies, recognized in 11 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,000+ studies for 60+ treatments. c19early.org
Retrospective 977 hospitalized patients in Saudi Arabia, showing significantly shorter hospitalization with zinc treatment.
hospitalization time, 30.2% lower, relative time 0.70, p < 0.001, treatment mean 6.39 (±0.76) n=130, control mean 9.15 (±0.27) n=847.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Alahmari et al., 27 Jun 2022, retrospective, Saudi Arabia, peer-reviewed, 7 authors, study period 1 May, 2020 - 30 July, 2020. Contact: a.alahmari@psau.edu.sa (corresponding author), z.almalki@psau.edu.sa, aa.albassam@psau.edu.sa, ah.alshehri@psau.edu.sa, n.ahmed@psau.edu.sa, mmaalsultan@iau.edu.sa, ph.abdalhadi@gmail.com.
This PaperZincAll
Factors Associated with Length of Hospital Stay among COVID-19 Patients in Saudi Arabia: A Retrospective Study during the First Pandemic Wave
Abdullah K Alahmari, Ziyad S Almalki, Ahmed A Albassam, Mohammed M Alsultan, Ahmed M Alshehri, Nehad J Ahmed, Abdulhadi M Alqahtani
Healthcare, doi:10.3390/healthcare10071201
The COVID-19 pandemic severely affected healthcare systems and tested their preparedness. To date, the length of hospital stay (LoHS) and its factors among COVID-19 patients has not been thoroughly studied. Moreover, it is essential to identify the features of these patients. Adult COVID-19 patients in Saudi Arabia with complete electronic medical records and who were hospitalised for >1 day between 1 May 2020 and 30 July 2020 at one of two hospitals were considered for this retrospective cohort study. Descriptive statistics and multivariate generalized linear models were performed using the data. Of the patients, 34% were ≥50 years old and 80.14% were female. More than 70% had mild-to-moderate symptoms; 45% had either diabetes or hypertension. The median LoHS was 7.00 days (IQR: 3-11). Patients who were females, had either critical or severe disease, were on mechanical ventilation, had diabetes, and administered ceftriaxone had significantly longer LoHS (p < 0.05). Patients administered zinc sulphate had significantly shorter LoHS (p = 0.0008). During the first pandemic wave, COVID-19 patients were hospitalised for 7 days. Healthcare professionals should pay more attention to women, patients with diabetes, and those with severe or critical symptoms. Unnecessary use of ceftriaxone should be minimised, and zinc sulphate can be administered.
References
Abate, Kassie, Kassaw, Aragie, Masresha, Sex Difference in Coronavirus Disease (COVID-19): A Systematic Review and Meta-Analysis, BMJ Open, doi:10.1136/bmjopen-2020-040129
Abougazia, Alnuaimi, Mahran, Ali, Khedr et al., Chest X-ray Findings in COVID-19 Patients Presenting to Primary Care during the Peak of the First Wave of the Pandemic in Qatar: Their Association with Clinical and Laboratory Findings, Pulm. Med, doi:10.1155/2021/4496488
Adebisi, Jimoh, Ogunkola, Uwizeyimana, Olayemi et al., The Use of Antibiotics in COVID-19 Management: A Rapid Review of National Treatment Guidelines in 10 African Countries, Trop. Med. Health, doi:10.1186/s41182-021-00344-w
Alghamdi, Clinical Characteristics and Treatment Outcomes of severe (ICU) COVID-19 patients in Saudi Arabia: A Single Centre Study, Saudi Pharm. J, doi:10.1016/j.jsps.2021.08.008
Alguwaihes, Al-Sofiani, Megdad, Albader, Alsari et al., Diabetes and COVID-19 among Hospitalized Patients in Saudi Arabia: A Single-Centre Retrospective Study, Cardiovasc. Diabetol, doi:10.1186/s12933-020-01184-4
Alharbi, Alqahtani, Albalawi, Bakouri, Epidemiological Modeling of COVID-19 in Saudi Arabia: Spread Projection, Awareness, and Impact of Treatment, Appl. Sci, doi:10.3390/app10175895
Alharthy, Aletreby, Faqihi, Balhamar, Alaklobi et al., Clinical Characteristics and Predictors of 28-day Mortality in 352 Critically Ill Patients with COVID-19: A Retrospective Study, J. Epidemiol. Glob. Health, doi:10.2991/jegh.k.200928.001
Alqahtani, Almalki, Alalweet, Almazrou, Alanazi et al., Assessing the Severity of Illness in Patients with Coronavirus Disease in Saudi Arabia: A Retrospective Descriptive Cross-Sectional Study, Front. Public Health, doi:10.3389/fpubh.2020.593256
Alqassieh, Bsisu, Al-Sabbagh, El-Hammuri, Yousef et al., Clinical Characteristics and Predictors of the Duration of Hospital Stay in COVID-19 Patients in Jordan [version 1; peer review: 1 approved with reservations, 1 not approved, doi:10.12688/f1000research.27419.1
Alsofayan, Althunayyan, Khan, Hakawi, Assiri, Clinical Characteristics of COVID-19 in Saudi Arabia: A National Retrospective Study, J. Infect. Public Health, doi:10.1016/j.jiph.2020.05.026
Alwafi, Naser, Qanash, Brinji, Ghazawi et al., Predictors of Length of Hospital Stay, Mortality, and Outcomes among Hospitalised COVID-19 Patients in Saudi Arabia: A Cross-Sectional Study, J. Multidiscip. Healthc, doi:10.2147/JMDH.S304788
Billett, Reyes-Gil, Szymanski, Ikemura, Stahl et al., Anticoagulation in COVID-19: Effect of Enoxaparin, Heparin, and Apixaban on Mortality, Thromb. Haemost, doi:10.1055/s-0040-1720978
Cai, Xu, Lin, Yang, Xu et al., A Case Series of Children with 2019 Novel Coronavirus Infection: Clinical and Epidemiological Features, Clin. Infect. Dis, doi:10.1093/cid/ciaa198
Caramelo, Ferreira, Oliveiros, Estimation of Risk Factors for COVID-19 Mortality-Preliminary Results, MedRxiv, doi:10.1101/2020.02.24.20027268
Chedid, Waked, Haddad, Chetata, Saliba et al., Antibiotics in Treatment of COVID-19 Complications: A Review of Frequency, Indications, and Efficacy, J. Infect. Public Health, doi:10.1016/j.jiph.2021.02.001
Chen, Zhang, Yang, Wang, Zhai et al., Fangcang Shelter Hospitals: A Novel Concept for Responding to Public Health Emergencies, Lancet, doi:10.1016/S0140-6736(20)30744-3
Chen, Zhou, Dong, Qu, Gong et al., Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study, Lancet
Chitungo, Dzinamarira, Nyazika, Herrera, Musuka et al., Inappropriate antibiotic use in Zimbabwe in the COVID-19 Era: A perfect recipe for antimicrobial resistance, Antibiotics, doi:10.3390/antibiotics11020244
Dong, Mo, Hu, Qi, Jiang et al., Epidemiology of COVID-19 Among Children in China, Pediatrics, doi:10.1542/peds.2020-0702
Dowd, Andriano, Brazel, Rotondi, Block et al., Demographic Science Aids in Understanding the Spread and Fatality Rates of COVID-19, doi:10.1073/pnas.2004911117
Estrada, Calderón Parra, Fernández Carracedo, Muiño Míguez, Ramos Martínez et al., Inadequate use of antibiotics in the COVID-19 era: Effectiveness of antibiotic therapy, BMC Infect. Dis, doi:10.1186/s12879-021-06821-1
Guo, Lu, Tan, Kuang, Luo et al., Risk Factors on Admission Associated with Hospital Length of Stay in Patients with COVID-19: A Retrospective Cohort Study, Sci. Rep, doi:10.1038/s41598-021-86853-4
Huang, Wang, Li, Ren, Zhao et al., Clinical Features of Patients Infected with 2019 Novel Coronavirus in Wuhan, China, Lancet, doi:10.1016/S0140-6736(20)30183-5
Jin, Bai, He, Wu, Liu et al., Gender Differences in Patients with COVID-19: Focus on Severity and Mortality, Front. Public Health, doi:10.3389/fpubh.2020.00152
Jombart, Procter, Knight, COVID-19 Length of Hospital Stay: A Systematic Review and Data Synthesis, BMC Med
Killerby, Link-Gelles, Haight, Schrodt, England et al., Characteristics Associated with Hospitalization Among Patients with COVID-19-Metropolitan Atlanta, Georgia, Morb. Mortal. Wkly. Rep, doi:10.15585/mmwr.mm6925e1
Leal, Yu, Chen, Fedele, Martins, Paracetamol is Associated with a Lower Risk of COVID-19 Infection and Decreased ACE2 Protein Expression: A Retrospective Analysis, COVID, doi:10.3390/covid1010018
Mahboub, Al Bataineh, Alshraideh, Hamoudi, Salameh et al., Prediction of COVID-19 Hospital Length of Stay and Risk of Death Using Artificial Intelligence-Based Modeling, Front. Med, doi:10.3389/fmed.2021.592336
Petrosillo, Viceconte, Ergonul, Ippolito, Petersen, COVID-19, SARS and MERS: Are They Closely Related?, Clin. Microbiol. Infect, doi:10.1016/j.cmi.2020.03.026
Phua, Weng, Ling, Egi, Lim et al., Intensive Care Management of Coronavirus Disease 2019 (COVID-19): Challenges and Recommendations, Lancet Respir. Med, doi:10.1016/S2213-2600(20)30161-2
Rees, Nightingale, Jafari, Waterlow, Clifford et al., None
Sanyaolu, Okorie, Marinkovic, Patidar, Younis et al., Comorbidity and its impact on patients with COVID-19, SN Compr. Clin. Med, doi:10.1007/s42399-020-00363-4
Shareef, Bakouri, Cytokine Blood Filtration Responses in COVID-19, Blood Purif, doi:10.1159/000508278
Singh, Malik, Patel, Pothuru, Israni et al., Kidney disease and COVID-19 disease severity-Systematic review and meta-analysis, Clin. Exp. Med, doi:10.1007/s10238-021-00715-x
Skalny, Rink, Ajsuvakova, Aschner, Gritsenko et al., Zinc and Respiratory Tract Infections: Perspectives for COVID19 (Review), Int. J. Mol. Med
Tang, Bai, Chen, Gong, Li et al., Anticoagulant Treatment is Associated with Decreased Mortality in Severe Coronavirus Disease 2019 Patients with Coagulopathy, J. Thromb. Haemostasis, doi:10.1111/jth.14817
Tenforde, Rose, Lindsell, Shapiro, Files et al., Characteristics of Adult Outpatients and Inpatients with COVID-19-11 Academic Medical Centers, Morb. Mortal. Wkly. Rep, doi:10.15585/mmwr.mm6926e3
Vekaria, Overton, Wiśniowski, Ahmad, Aparicio-Castro et al., Hospital Length of Stay for COVID-19 Patients: Data-Driven Methods for Forward Planning, BMC Infect. Dis, doi:10.1186/s12879-021-06371-6
Verity, Okell, Dorigatti, Winskill, Whittaker et al., Estimates of the Severity of Coronavirus Disease 2019: A Model-Based Analysis, Lancet Infect. Dis, doi:10.1016/S1473-3099(20)30243-7
Wang, Liu, Wei, Ji, Liu et al., What are the Risk Factors of Hospital Length of Stay in the Novel Coronavirus Pneumonia (COVID-19) Patients? A Survival Analysis in Southwest China, PLoS ONE, doi:10.1371/journal.pone.0261216
Wessels, Rolles, Rink, The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis, Front. Immunol, doi:10.3389/fimmu.2020.01712
Who, Coronavirus Disease (COVID-19) Advice for the Public: Mythbusters
Worldometer, None
Wu, Mcgoogan, Characteristics of and Important Lessons from the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases from the Chinese Center for Disease Control and Prevention, J. Am. Med. Assoc, doi:10.1001/jama.2020.2648
Xing, Zhang, COVID-19 in China: Responses, Challenges and Implications for the Health System, Healthcare, doi:10.3390/healthcare9010082
Yasui, Yasui, Suzuki, Saitou, Yamamoto et al., Analysis of the Predictive Factors for a Critical Illness of COVID-19 During Treatment-Relationship between Serum Zinc Level and Critical Illness of COVID-19, Int. J. Infect. Dis, doi:10.1016/j.ijid.2020.09.008
Zhou, Yu, Du, Fan, Liu et al., Clinical Course and Risk Factors for Mortality of Adult Inpatients with COVID-19 in Wuhan, China: A Retrospective Cohort Study, Lancet
Álvarez-Esteban, Del Barrio, Rueda, Rueda, Predicting COVID-19 Progression from Diagnosis to Recovery or Death Linking Primary Care and Hospital Records in Castilla y León (Spain), PLoS ONE, doi:10.1371/journal.pone.0257613
Late treatment
is less effective
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